ListoPedia

Pathogen Interactions

This dataset contains information about various pathogens, specifically detailing their types, target organisms, interactions with hosts, mechanisms of action, effects on health, and modes of transmission. The first 10 rows illustrate a range of bacterial, viral, and protozoan pathogens that primarily affect humans, emphasizing the diversity in their mechanisms and the associated health risks.
  • Pathogen: The name of the organism causing disease, which can be a bacterium, virus, or protozoan.
  • Type: The classification of the pathogen, indicating whether it is a bacterium, virus, or protozoan.
  • Target Organism: The organism that is affected by the pathogen, typically humans in this dataset.
  • Interaction Type: The nature of the interaction between the pathogen and the host, often describing the type of disease or condition caused.
  • Mechanism: The biological process by which the pathogen causes disease or disrupts normal bodily functions.
  • Effects: The health consequences or illnesses resulting from the pathogen's action on the host.
  • Transmission Mode: The ways in which the pathogen can spread from one host to another, specifying routes of infection.

Download Files

CSVMDTXTHTML
XMLODSPDFXLSX
YAMLTSVJSON

Sample Data

Pathogen Type Target Organism Interaction Type Mechanism Effects Transmission Mode
Bacillus anthracis Bacterium Human Infection Spore formation Severe illness, potential death Inhalation, ingestion, cutaneous
Escherichia coli O157:H7 Bacterium Human Infection Shiga toxin production Gastroenteritis Foodborne, waterborne
Staphylococcus aureus Bacterium Human Infection Toxin production Skin infections, food poisoning Direct contact, aerosol
Streptococcus pneumoniae Bacterium Human Infection Capsule production Pneumonia, meningitis Person-to-person
Clostridium tetani Bacterium Human Toxin production Neurotoxin production Tetanus Wound contamination
Plasmodium falciparum Protozoan Human Parasitemia Invasion of red blood cells Malaria Mosquito bite
Human Immunodeficiency Virus Virus Human Infection Targeting CD4+ T cells AIDS Sexual contact, blood exposure
Influenza virus Virus Human Infection Cellular entry via HA Respiratory illness Aerosol transmission
Zika virus Virus Human Infection Neurotropism Fetal abnormalities, fever Mosquito bite, sexual contact
Salmonella enterica Bacterium Human Infection Invasion of intestinal cells Gastroenteritis Foodborne, waterborne
Helicobacter pylori Bacterium Human Infection Urease production Peptic ulcers, gastric cancer Oral-oral, fecal-oral
Neisseria meningitidis Bacterium Human Infection Polysaccharide capsule Meningitis, sepsis Respiratory droplets
Vibrio cholerae Bacterium Human Infection Cholera toxin production Severe diarrhea, dehydration Waterborne
Human Papillomavirus Virus Human Infection Oncogenic potential Cervical cancer Sexual contact
Rabies virus Virus Human Infection Neuroinvasion Rabies Animal bite
Chlamydia trachomatis Bacterium Human Infection Intracellular replication STI, infertility Sexual contact
Borrelia burgdorferi Bacterium Human Infection Spiral shape, motility Lyme disease Tick bite
Candida albicans Fungus Human Infection Biofilm formation Candidiasis Opportunistic, endogenous
Brucella spp. Bacterium Human Infection Intracellular replication Brucellosis Ingestion of contaminated food
Mycobacterium tuberculosis Bacterium Human Infection Slow growth, cell wall lipids Tuberculosis Airborne
Trichomonas vaginalis Protozoan Human Infection Flagellar motility Trichomoniasis Sexual contact
Zygomycetes Fungus Human Infection Angioinvasion Mucormycosis Opportunistic, inhalation
Chikungunya virus Virus Human Infection Replication in muscle cells Fever, arthralgia Mosquito bite
Dengue virus Virus Human Infection Affects endothelial cells Dengue fever Mosquito bite
Rhinovirus Virus Human Infection Receptor-mediated endocytosis Common cold Aerosol transmission
Adenovirus Virus Human Infection Viral replication Respiratory infections, conjunctivitis Aerosol, fomites
West Nile virus Virus Human Infection Neuroinvasive potential Encephalitis Mosquito bite
Ebola virus Virus Human Infection Direct viral replication in host Hemorrhagic fever Contact with bodily fluids
SARS-CoV-2 Virus Human Infection Spike protein-mediated entry COVID-19 Airborne, contact
Yersinia pestis Bacterium Human Infection Type III secretion system Bubonic plague Flea bite, respiratory droplet
Listeria monocytogenes Bacterium Human Infection Intracellular growth Gastroenteritis, meningitis Foodborne
Shigella flexneri Bacterium Human Infection Shiga toxin production Dysentery Fecal-oral transmission
Enterobius vermicularis Helminth Human Infection Egg transmission Pinworm infection Fecal-oral transmission
Clonorchis sinensis Helminth Human Infection Liver damage Choleriasis Foodborne (eating raw fish)
Schistosoma mansoni Helminth Human Infection Invasion through skin Schistosomiasis Contact with contaminated water
Trypanosoma brucei Protozoan Human Infection CNS invasion African sleeping sickness Tsetse fly bite
Entamoeba histolytica Protozoan Human Infection Tissue invasion Amoebic dysentery Fecal-oral transmission
Streptococcus pyogenes Bacterium Human Infection M protein evasion Pharyngitis, necrotizing fasciitis Direct contact, respiratory droplets
Coxsackievirus Virus Human Infection Cytolytic activity Hand, foot, and mouth disease Fecal-oral route
Parvovirus B19 Virus Human Infection Bone marrow infection Fifth disease Respiratory secretions
Hepatitis A virus Virus Human Infection Oral-fecal route Hepatitis Fecal-oral transmission
Hepatitis B virus Virus Human Infection Chronic liver infection Hepatitis, cancer Blood, sexual contact
Hepatitis C virus Virus Human Infection Chronic liver infection Hepatitis, liver failure Blood, sexual contact
Cryptosporidium parvum Protozoan Human Infection Intracellular parasitism Cryptosporidiosis Waterborne, fecal-oral
Neisseria gonorrhoeae Bacterium Human Infection Hormonal modulation Gonorrhea Sexual contact
Legionella pneumophila Bacterium Human Infection Intracellular growth Legionnaires' disease Aerosol transmission
Yersinia enterocolitica Bacterium Human Infection Invasion of mucosa Gastroenteritis Foodborne
Francisella tularensis Bacterium Human Infection Intracellular replication Tularemia Direct contact, vector-borne
Chlamydophila psittaci Bacterium Human Infection Intracellular replication Psittacosis Aerosol transmission
Hantavirus Virus Human Infection Vascular permeability Hantavirus pulmonary syndrome Rodent excretions
Q fever (Coxiella burnetii) Bacterium Human Infection Intracellular survival Q fever Aerosol transmission
Fusobacterium necrophorum Bacterium Human Infection Toxin production Lemierre's syndrome Normal flora opportunistic
Pseudomonas aeruginosa Bacterium Human Infection Biofilm formation Pulmonary infections Opportunistic pathogen
Clostridium difficile Bacterium Human Infection Toxin A and B production Antibiotic-associated diarrhea Fecal-oral route
Treponema pallidum Bacterium Human Infection Intracellular survival Syphilis Sexual contact
Anaplasma phagocytophilum Bacterium Human Infection Intracellular replication Human granulocytic anaplasmosis Tick bite
Neorickettsia sennetsu Bacterium Human Infection Intracellular replication Sennetsu fever Contact with water contaminated by fish
Chlamydia psittaci Bacterium Human Infection Intracellular replication Psittacosis Aerosols from infected birds
Rickettsia rickettsii Bacterium Human Infection Intracellular replication Rocky Mountain spotted fever Tick bite
Enterobacter sakazakii Bacterium Human Infection Neonatal infections Meningitis Contaminated infant formula
Bradyhizobium spp. Bacterium Plant Symbiosis Nitrogen fixation Improved growth in legumes Root nodules formation
Rhizobium spp. Bacterium Plant Symbiosis Nitrogen fixation Enhanced nutrient uptake Root nodules of legumes
Agrobacterium tumefaciens Bacterium Plant Genetic transformation Crown gall disease Tumor-like growth Plant wound infection
Mycobacterium leprae Bacterium Human Infection Slow replication Leprosy Prolonged close contact
Orientia tsutsugamushi Bacterium Human Infection Intracellular growth Scrub typhus Rodent mites
Histoplasma capsulatum Fungus Human Infection Intracellular growth Histoplasmosis Aerosol transmission from bird droppings
Blastomyces dermatitidis Fungus Human Infection Inhalation of spores Blastomycosis Aerosol transmission
Coccidioides immitis Fungus Human Infection Inhalation of arthroconidia Valley fever Aerosol transmission
Paracoccidioides brasiliensis Fungus Human Infection Inhalation of spores Paracoccidioidomycosis Aerosol transmission
Cryptococcus neoformans Fungus Human Infection Encapsulation Meningitis Aerosol transmission from bird feces
Penicillium marneffei Fungus Human Infection Intracellular growth Penicilliosis Aerosol transmission in endemic areas
Candida auris Fungus Human Infection Drug resistance Invasive candidiasis Direct contact
Nocardia asteroides Bacterium Human Infection Opportunistic pathogen Nocardiosis Inhalation, contamination of wounds
Acanthamoeba castellanii Protozoan Human Infection Contact lens contamination Acanthamoeba keratitis Direct contact with contaminated water
Varicella-zoster virus Virus Human Infection Latency in neurons Chickenpox, shingles Respiratory droplets
Cytomegalovirus Virus Human Infection Cell-mediated immunity evasion Congenital infections Saliva, transplants
Venezuelan equine encephalitis virus Virus Human Infection Neurotropic infection Encephalitis Mosquito bite
Junin virus Virus Human Infection Zoonotic transmission Argentine hemorrhagic fever Contact with rodent excretions
Marburg virus Virus Human Infection Infects multiple cell types Marburg virus disease Contact with bodily fluids
Nipah virus Virus Human Infection Direct viral replication Nipah virus infection Fruit bats, contaminated food
Crimean-Congo hemorrhagic fever virus Virus Human Infection Invasion of endothelial cells CCHF Tick bites, contact
Rift Valley fever virus Virus Human Infection Zoonotic transmission Rift valley fever Mosquito bites, livestock contact
Blue tongue virus Virus Animal Infection Vascular damage Bluetongue disease Insect bites (biting midges)
Foot-and-mouth disease virus Virus Animal Infection Cell lysis Vesicular disease in cloven-hoofed animals Contact, aerosol
Classical swine fever virus Virus Animal Infection Immunosuppression Hog cholera Contact with infected animals
Avian influenza virus Virus Animal Infection Respiratory infection Bird flu Contact with infected birds
Porcine reproductive and respiratory syndrome virus Virus Animal Infection Types of immune evasion PRRS Aerosol, contact
Newcastle disease virus Virus Animal Infection Viral replication in lungs Respiratory disease in birds Contact, aerosol
Marek's disease virus Virus Animal Infection Changes in lymphocytes Lymphoid tumors in poultry Contact with infected birds
Canine parvovirus Virus Animal Infection Rapid replication in dividing cells Vomiting, diarrhea Contact with infected feces
Feline leukemia virus Virus Animal Infection Immunosuppression Feline leukemia Bite, grooming
Lentivirus Virus Animal Infection Infection of immune cells Feline immunodeficiency virus Bite, grooming
Canine distemper virus Virus Animal Infection Neurological involvement Distemper in dogs Contact, aerosol
Rabies virus Virus Animal Infection Neurotropic infection Rabies in mammals Bite from infected animals
Western equine encephalitis virus Virus Animal Infection Neurotropic strain Western equine encephalitis Mosquito bite
Japanese encephalitis virus Virus Animal Infection Neuroinvasion Japanese encephalitis Mosquito bite
Equine encephalitis virus Virus Animal Infection Neuroinvasive potential Equine encephalitis Mosquito transmission
Severe acute respiratory syndrome virus Virus Human Infection Respiratory distress SARS Respiratory droplets
MERS-CoV Virus Human Infection Respiratory infection Middle East respiratory syndrome Contact, aerosol
Rising virus Virus Human Infection Promotes immune evasion Rising disease Vector transmission
Chlamydia psittaci Bacterium Human Infection Intracellular replication Psittacosis Aerosol from bird droppings
Stenotrophomonas maltophilia Bacterium Human Infection Biofilm production Pulmonary infections Opportunistic pathogen
Acinetobacter baumannii Bacterium Human Infection Multidrug resistance Nosocomial infections Direct contact
Salmonella typhi Bacterium Human Infection Typhoid toxin production Typhoid fever Fecal-oral transmission
Toxoplasma gondii Protozoan Human Infection Intracellular growth Toxoplasmosis Fecal-oral, zoonotic
Mycoplasma pneumoniae Bacterium Human Infection Adhesion to respiratory epithelium Atypical pneumonia Respiratory droplets
Propionibacterium acnes Bacterium Human Infection Biofilm formation Acne vulgaris Normal skin flora
Rickettsia prowazekii Bacterium Human Infection Intracellular replication Epidemic typhus Louse bites
Anaplasma phagocytophilum Bacterium Human Infection Evasion of immune response Human granulocytic anaplasmosis Tick bite
Chlamydia caviae Bacterium Human Infection Intracellular replication Respiratory infections Indirect contact with guinea pigs
Adenovirus 5 Virus Human Infection Receptor-mediated endocytosis Conjunctivitis, respiratory infections Fomites, aerosol
Rhinovirus 14 Virus Human Infection Infection of upper respiratory tract Common cold Aerosol, contact
Multidrug-resistant Mycobacterium tuberculosis Bacterium Human Infection Drug resistance mechanisms Multidrug-resistant tuberculosis Airborne
Campylobacter jejuni Bacterium Human Infection S-shaped form enhances mobility Gastroenteritis Foodborne, waterborne
Clostridium perfringens Bacterium Human Infection Toxin production Food poisoning Foodborne
Bordetella pertussis Bacterium Human Infection Toxin production Whooping cough Airborne
Equine herpesvirus 1 Virus Animal Infection Respiratory infection Equine abortion Contact, aerosol
Equine influenza virus Virus Animal Infection Respiratory disease Equine influenza Contact, aerosol
Canine coronavirus Virus Animal Infection Gastrointestinal illness Canine enteritis Contact, fecal-oral
Feline infectious peritonitis virus Virus Animal Infection Immune response dysregulation FIP Contact, aerosol
Porcine parvovirus Virus Animal Infection Reproductive failure Porcine reproductive disease Contact, aerosol
Adenovirus 2 Virus Animal Infection Causes respiratory disease Kennel cough Contact, aerosol
Leptospira interrogans Bacterium Human Infection Invasion of tissues Leptospirosis Waterborne, zoonotic
Borrelia hermsii Bacterium Human Infection Direct bloodstream invasion Relapsing fever Tick bite
Yersinia pestis (flea-borne) Bacterium Human Infection Intracellular growth Plague Flea bites
Toxocara canis Helminth Human Infection Visceral larva migrans Toxocariasis Fecal-oral transmission
Enterobius vermicularis (pinworm) Helminth Human Infection Egg ingestion Pinworm infection Fecal-oral transmission
Pneumocystis jirovecii Fungus Human Infection Opportunistic pathogen Pneumocystis pneumonia Aerosol transmission
Giardia lamblia Protozoan Human Infection Fecal-oral transmission Giardiasis Waterborne, fecal-oral
Babesia microti Protozoan Human Infection Invasion of red blood cells Babesiosis Tick bite
Cryptosporidium hominis Protozoan Human Infection Intracellular growth in intestine Cryptosporidiosis Waterborne, fecal-oral
Legionella longbeachae Bacterium Human Infection Aerosolized bacteria Legionnaires' disease Contact with contaminated water
Bartonella henselae Bacterium Human Infection Intracellular growth Cat scratch fever Cat scratches or bites
Francisella tularensis (e.g., type A) Bacterium Human Infection Intracellular growth Tularemia Contact with infected animals
Hepatitis D virus Virus Human Infection Requires co-infection with HBV Severe liver disease Blood, sexual contact
Hantaan virus Virus Human Infection Infiltration of pulmonary cells Hemorrhagic fever Rodent excrement
Junin virus Virus Human Infection Zoonotic disease transmission Argentine hemorrhagic fever Contact with infected rodents
Machupo virus Virus Human Infection Severely infects blood vessels Bolivian hemorrhagic fever Contact with infected rodents
Sabia virus Virus Human Infection Receptor-mediated entry into cells Hemorrhagic fever Contact with wild animals
Trichinella spiralis Helminth Human Infection Ingestion of larvae in undercooked meat Trichinosis Foodborne
Echinococcus granulosus Helminth Human Infection Formation of cysts Hydatid disease Fecal-oral, zoonotic
Echinococcus multilocularis Helminth Human Infection Formation of multivesicular cysts Alveolar echinococcosis Zoonotic
Back to Main Page