The dataset consists of information about various gene editing technologies, detailing their introduction dates, descriptions, and potential applications. It highlights innovations in the field of genetic engineering and their diverse uses from medicine to agriculture.
| Technology | Type | Year Introduced | Description | Applications |
|---|---|---|---|---|
| CRISPR-Cas9 | Gene Editing | 2012 | A powerful tool that allows for precise modifications in the DNA of organisms. | Medicine, Agriculture |
| Zinc Finger Nucleases (ZFNs) | Gene Editing | 2010 | Designed to create double-strand breaks in DNA at specific sites. | Gene therapy, Crop improvement |
| TALENs (Transcription Activator-Like Effector Nucleases) | Gene Editing | 2011 | Engineered proteins that can cut DNA at specified locations, similar to ZFNs. | Genetic modification, Therapeutics |
| Base Editing | Gene Editing | 2016 | Enables the conversion of one DNA base into another without causing double-strand breaks. | Curing genetic diseases, Precision medicine |
| Prime Editing | Gene Editing | 2019 | Offers a versatile and precise method for directly rewriting DNA sequences. | Gene therapy, Genetic engineering |
| CRISPR-Cas12 | Gene Editing | 2017 | A novel CRISPR system that offers improved specificity and reduced off-target effects. | Diagnostics, Genetic modification |
| Gene Drives | Gene Editing | 2015 | A method to spread genetic alterations through populations, affecting inheritance patterns. | Pest control, Conservation biology |
| CRISPRi/CRISPRa | Gene Editing | 2013 | CRISPR-based techniques to inhibit or activate gene expression without editing DNA. | Gene regulation, Research |
| RNA-guided Gene Editing | Gene Editing | 2019 | Uses RNA molecules to guide editing enzymes to specific locations in the genome. | Farmland yield enhancements, Medical research |
| Epigenome Editing | Gene Editing | 2016 | Techniques that allow for modifications to the epigenome and gene expression without changing DNA. | Research, Therapeutics |
| SmRNA Molecules | Gene Editing | 2017 | Short modular RNA sequences used to target specific mRNA for degradation. | Gene silencing, Precision therapeutics |
| Transgene-free Nucleases | Gene Editing | 2020 | Methods to edit the genome without leaving foreign DNA behind. | Agriculture, Gene therapy |
| Gene Editing with Artificial Intelligence | Gene Editing | 2021 | Integration of AI algorithms with gene-editing techniques to predict outcomes and optimize edits. | Research, Drug discovery |
| CRISPR-Cas9 in T cells | Gene Editing | 2014 | Adapting CRISPR-Cas9 technology to edit T cells for immunotherapy applications. | Cancer treatment, Transplantation |
| XNA (Xeno Nucleic Acids) Technology | Gene Editing | 2021 | Incorporating synthetic bases into genetics to improve stability and functionality. | Synthetic biology, Therapeutics |
| Nanoediting | Gene Editing | 2018 | Utilizing nanoparticles to deliver gene-editing tools directly into cells with high efficiency. | Drug delivery, Genetic modification |
| Epigenetic therapies | Gene Editing | 2020 | Targeting the epigenetic modifications to alter gene expression for therapeutic purposes. | Cancer, Neurological disorders |
| CRISPR-based diagnostics | Gene Editing | 2016 | Leveraging CRISPR technology for rapid and accurate disease diagnostics. | Infectious diseases, Genetic testing |
| Microbiome Gene Editing | Gene Editing | 2019 | Editing the genetic material of microbiomes to enhance health benefits. | Gut health, Probiotics |
| Cloud-based Gene Editing Services | Gene Editing | 2022 | Platforms providing gene-editing tools and simulations via cloud computing. | Research, Education |
| Plant Gene Editing with CRISPR | Gene Editing | 2016 | Using CRISPR to improve crop resilience, nutritional value, and yield. | Agricultural biotechnology |
| CRISPR for Sickle Cell Disease | Gene Editing | 2020 | Therapeutic applications of CRISPR/Cas9 to correct hemoglobin mutations. | Genetic disorders, Hematology |
| Genome Sequencing Combined with Editing | Gene Editing | 2018 | Integrating sequencing technology with editing to continuously refine genetic manipulations. | Precision medicine, Research |
| Genome-wide association studies (GWAS) integration | Gene Editing | 2019 | Using GWAS to inform gene editing targets and improve precision. | Healthcare, Gene therapy |
| CRISPR-Cas13 for RNA editing | Gene Editing | 2018 | Editing RNA directly instead of DNA, using the CRISPR-Cas13 system. | Viral inhibition, Gene regulation |
| Lentiviral vectors in Gene Editing | Gene Editing | 2010 | Viral vectors used to deliver editing tools into target cells effectively. | Gene therapy, Genetic research |
| CRISPR-Cas9 in agriculture | Gene Editing | 2015 | Application of CRISPR-Cas9 for developing genetically modified crops. | Sustainable agriculture, Crop engineering |
| Nano-Cas9 delivery systems | Gene Editing | 2019 | Using nanotechnology to enhance delivery of CRISPR-Cas9 into cells. | Gene therapy, Cancer treatment |
| Chromatin-targeting CRISPR | Gene Editing | 2019 | Directing CRISPR systems to specific chromatin structures to modify gene regulation. | Gene therapy, Research |
| CRISPR-mediated epigenetic modulation | Gene Editing | 2016 | Utilizing CRISPR technology to induce targeted epigenetic modifications. | Therapeutics, Research |
| Biosecurity approaches in Gene Editing | Gene Editing | 2020 | Developing safety protocols for gene editing technologies to prevent misuse. | Bioethics, Policy-making |
| Gene Editing for Cystic Fibrosis | Gene Editing | 2022 | Application of gene editing technologies to address genetic mutations associated with cystic fibrosis. | Gene therapy, Healthcare |
| CRISPR for Huntington's disease | Gene Editing | 2021 | Utilization of CRISPR technology to modify genes associated with Huntington's disease. | Therapeutics, Neurology |
| CRISPR-based plant secondary metabolite engineering | Gene Editing | 2022 | Editing genes related to secondary metabolites in plants to improve medicinal properties. | Agricultural biotechnology, Pharmacology |
| Self-limiting Gene Drives | Gene Editing | 2018 | Gene drives designed to reduce their own spread over time to control ecological disruptions. | Ecology, Conservation |
| Antisense Oligonucleotides with Editing | Gene Editing | 2019 | Novel techniques combining oligonucleotides with CRISPR for precise editing of RNA and DNA. | Gene therapy, Neurology |
| CRISPR for gene therapy in mouse models | Gene Editing | 2014 | Initial use of CRISPR to demonstrate effective gene editing in mouse models for disease research. | Research, Genetic modification |
| Virtual Reality for Gene Editing Education | Gene Editing | 2021 | Using virtual reality platforms to train students and researchers in gene editing techniques. | Education, Research training |
| CRISPR for Immuno-Oncology | Gene Editing | 2021 | Applying CRISPR technology to enhance immune responses against cancer cells. | Cancer therapy, Immunotherapy |
| Next-Generation Sequencing (NGS) with Editing | Gene Editing | 2017 | Combining NGS with gene editing to enable precise genomic analysis. | Research, Diagnostics |
| Bioprinting with Gene Editing | Gene Editing | 2022 | Using gene editing in combination with bioprinting technology to create living tissues. | Tissue engineering, Regenerative medicine |
| CRISPR-enhanced phage therapy | Gene Editing | 2020 | Using CRISPR technology to improve the efficacy of bacteriophage treatments for infections. | Microbiology, Therapeutics |
| Targeted RNA degradation with CRISPR | Gene Editing | 2018 | Developing methods to selectively degrade RNA transcripts to control gene expression. | Research, Gene therapy |
| Regulatory frameworks for gene editing | Gene Editing | 2019 | Establishing policies and regulations governing the use of gene editing technologies. | Bioethics, Legislation |
| CRISPR and microbiome engineering | Gene Editing | 2021 | Utilizing CRISPR to engineer beneficial microbiomes for health applications. | Health science, Research |
| CRISPR-assisted synthetic biology | Gene Editing | 2020 | Using CRISPR tools to enhance synthetic biology applications for novel organism design. | Synthetic biology, Biotechnology |
| Invivo gene editing using CRISPR | Gene Editing | 2017 | Applying CRISPR technology directly into living organisms for therapeutic interventions. | Therapeutics, Research |
| CRISPR for regenerative medicine | Gene Editing | 2020 | Utilizing CRISPR technology to promote healing and repair in tissues. | Regenerative medicine, Therapeutics |
| Patient-derived models for gene editing | Gene Editing | 2018 | Creating models from patient cells to optimize gene editing treatments for personalized medicine. | Healthcare, Research |
| Understanding off-target effects in gene editing | Gene Editing | 2021 | Research focused on identifying and minimizing unintended changes in the genome caused by editing. | Therapeutics, Research |
| CRISPR for muscular dystrophy treatment | Gene Editing | 2021 | Research on using CRISPR methods to address genetic causes of muscular dystrophy. | Gene therapy, Neurology |
| CRISPR in climate-resilient crops | Gene Editing | 2019 | Developing crops that can withstand climate challenges using gene editing techniques. | Agricultural biotechnology, Food security |
| 3D modeling of genome editing pathways | Gene Editing | 2020 | Employing 3D modeling to visualize and understand gene editing processes and their effects. | Research, Education |
| Using AI to predict gene editing outcomes | Gene Editing | 2021 | Applying machine learning algorithms to anticipate the effects of gene editing modifications. | Research, Genomics |
| Public perceptions of gene editing technologies | Gene Editing | 2021 | Studying how different populations view and understand gene editing and its implications. | Survey, Policy study |
| CRISPR for disease-resistant plants | Gene Editing | 2019 | Enhancing plants' natural resistance to diseases through targeted gene editing. | Agricultural biotechnology, Crop improvement |
| Therapeutic protein development using gene editing | Gene Editing | 2020 | Utilizing gene editing to produce therapeutic proteins for medical treatment. | Biotechnology, Therapeutics |
| Improving vaccine efficacy through gene editing | Gene Editing | 2021 | Using gene editing strategies to enhance the effectiveness of vaccines against diseases. | Vaccinology, Infectious diseases |
| Novel CRISPR systems discovery | Gene Editing | 2022 | Identifying new CRISPR variants with unique properties for different applications. | Genetic engineering, Research |
| CRISPR in fungal genetics | Gene Editing | 2018 | Applying CRISPR technology in research and modification of fungal species. | Microbiology, Biotechnology |
| Designing genetic circuits with CRISPR | Gene Editing | 2021 | Engineering genetic circuits using CRISPR for specific cellular functions in synthetic biology. | Synthetic biology, Genetic engineering |
| Revisional editing techniques | Gene Editing | 2019 | Developing methods to revise gene modifications after initial edits to ensure precision. | Gene therapy, Research |
| CRISPR diagnostics for plant pathogens | Gene Editing | 2020 | Using CRISPR technologies to identify and diagnose plant diseases effectively. | Agricultural biotechnology, Crop research |
| CRISPR-based therapeutics for liver diseases | Gene Editing | 2021 | Exploring CRISPR applications in treating genetic liver diseases through precise edits. | Gene therapy, Hepatology |
| CRISPR technology profiles in diverse species | Gene Editing | 2021 | Documenting and analyzing the application of CRISPR techniques across various organisms. | Research, Comparative genomics |
| Using CRISPR to improve industrial microorganisms | Gene Editing | 2020 | Enhancing microorganisms for industrial processes using gene editing techniques. | Biotechnology, Industry |
| Ethics of gene editing research | Gene Editing | 2018 | Discussing the ethical implications and societal impacts of gene editing technologies. | Bioethics, Policy development |
| CRISPR-mediated gene knockout innovations | Gene Editing | 2017 | Enhancing traditional knockout techniques using CRISPR for improved knockout studies. | Gene therapy, Research |
| CRISPR to combat antibiotic resistance | Gene Editing | 2021 | Studies on using CRISPR technologies to address genetic bases of antibiotic resistance in bacteria. | Microbiology, Healthcare |
| Genome-wide CRISPR screens | Gene Editing | 2016 | Utilizing CRISPR for large-scale screening of genes that impact cellular phenotypes. | Research, Genomics |
| CRISPR and gene therapy production pipelines | Gene Editing | 2020 | Strategies for producing CRISPR-modified therapeutic products in a commercial setting. | Biotechnology, Therapeutics |
| Lessons from gene editing clinical trials | Gene Editing | 2021 | Analyzing outcomes and lessons learned from clinical trials using gene editing in patients. | Research, Epidemiology |
| CRISPR-enhanced cellular reprogramming | Gene Editing | 2019 | Using CRISPR technology to induce cellular reprogramming for therapeutic applications. | Regenerative medicine, Transplantation |
| Low-cost CRISPR kits for educational purposes | Gene Editing | 2022 | Developing affordable CRISPR kits to enhance education and public engagement in gene editing. | Education, Outreach |
| CRISPR technology's impact on agriculture | Gene Editing | 2021 | Evaluating how CRISPR technology is transforming agricultural practices and biosecurity. | Agricultural economy, Policy impact |
| CRISPR systems for non-model organisms | Gene Editing | 2018 | Adapting CRISPR techniques for application in species that are less characterized., | Research, Biodiversity |
| Genome editing in synthetic organisms | Gene Editing | 2021 | Engineering completely synthetic life forms through precise gene editing techniques. | Synthetic biology, Scientific research |
| CRISPR-Cas9 for treating genetic disorders | Gene Editing | 2020 | Clinical studies exploring the potential of CRISPR-Cas9 to address genetic disorders in humans. | Gene therapy, Clinical research |
| CRISPR-based tools for biodiversity conservation | Gene Editing | 2022 | Using gene editing tools to conserve endangered species and improve biodiversity. | Conservation biology, Ecology |
| CRISPR technology in non-viral gene delivery | Gene Editing | 2020 | Developing non-viral methods for delivering CRISPR components into target cells. | Gene therapy, Biotechnology |
| CRISPR manipulation of stem cells | Gene Editing | 2016 | Enhancing stem cell research and therapies through targeted gene editing methodologies. | Stem cell therapy, Regenerative medicine |
| Applications of CRISPR in plant breeding | Gene Editing | 2019 | Innovative approaches using CRISPR to accelerate plant breeding processes and varieties development. | Agricultural biotechnology, Crop improvement |
| Understanding gene editing impacts on ecosystems | Gene Editing | 2021 | Research focused on the ecological consequences of implementing gene editing technologies in nature. | Ecology, Conservation |
| Gene editing for arachnid research | Gene Editing | 2022 | Utilizing gene editing to study the genetics of spiders and other arachnids for various applications. | Research, Evolutionary biology |
| Use of soft robots in gene editing application | Gene Editing | 2020 | Integrating soft robotics in the delivery and operation of gene editing technologies in live experiments. | Biotechnology, Research |
| CRISPR for myocardial repair | Gene Editing | 2021 | Application of gene editing strategies aimed at repairing heart tissue and preventing disease. | Cardiology, Regenerative medicine |
| Cellular pathways optimization for gene editing | Gene Editing | 2021 | Optimizing cellular pathways to enhance efficiency and safety of gene editing techniques. | Research, Biotechnology |
| Tracing CRISPR application footprints | Gene Editing | 2019 | Tracking the application history and progress of CRISPR technology in various fields. | Research, Historical study |
| Building a public database for gene editing research | Gene Editing | 2022 | Initiating a platform for sharing data and findings related to gene editing studies globally. | Research, Data sharing |
| Comparative analysis of editing efficiencies | Gene Editing | 2021 | Studying the efficiency of various gene editing techniques across different organisms. | Research, Genomics |
| CRISPR for addressing rare genetic disorders | Gene Editing | 2020 | Investigating the potential of CRISPR to treat rare genetic diseases prevalent in specific populations. | Gene therapy, Policy research |
| Integrating gene editing with biomanufacturing | Gene Editing | 2019 | Combining gene editing techniques with biomanufacturing processes to enhance product yield. | Industry, Biotechnology |
| Perceptions of gene therapy in different cultures | Gene Editing | 2021 | Research on how cultural differences influence the understanding and acceptance of gene therapy. | Social study, Bioethics |
| CRISPR for gut microbiome modulation | Gene Editing | 2021 | Using CRISPR technologies to alter gut microbiota composition for health benefits. | Nutritional science, Microbiology |
| Real-time monitoring of gene editing outcomes | Gene Editing | 2022 | Employing modern techniques to monitor the effects of gene editing in real-time post-treatment. | Research, Biotechnology |
| Collaborative frameworks in gene editing research | Gene Editing | 2021 | Developing partnerships between academic institutions and industry for gene editing innovations. | Research, Collaboration |
| Novel drug delivery systems using gene editing | Gene Editing | 2020 | Creating innovative drug delivery methods incorporating CRISPR technologies for improved health outcomes. | Pharmaceuticals, Biotechnology |
| Augmented reality for gene editing learning | Gene Editing | 2022 | Utilizing augmented reality tools to enhance the understanding of gene editing concepts in educational settings. | Education, Technology |
| CRISPR in biomarker discovery | Gene Editing | 2021 | Using CRISPR technologies to identify and validate biomarkers for various diseases. | Research, Diagnostics |
| Genomic editing in wildlife conservation | Gene Editing | 2020 | Applying genomic editing methods to assist in the conservation of endangered species. | Conservation, Ecology |
| Minimizing ethical concerns in gene editing | Gene Editing | 2021 | Strategies for addressing the ethical dilemmas and concerns surrounding gene editing research and applications. | Bioethics, Policy framework |
| CRISPR for cancer immunotherapy | Gene Editing | 2021 | Utilizing CRISPR techniques to enhance the effectiveness of immunotherapeutic approaches in cancer treatment. | Oncology, Therapeutics |
| Exploring long-term effects of gene editing | Gene Editing | 2022 | Research into the long-term biological impacts of gene editing technologies in organisms. | Research, Safety assessment |
| Development of fusion proteins for editing | Gene Editing | 2019 | Creating specialized fusion proteins to improve the specificity of gene editing tools. | Biotechnology, Research |
| Ethical education in gene editing schools | Gene Editing | 2020 | Introducing programs to educate students about the ethics surrounding gene editing technologies. | Education, Bioethics |
| CRISPR technologies in Alzheimer's research | Gene Editing | 2021 | Investigating the applications of CRISPR in the study and potential treatment of Alzheimer's disease. | Neurology, Dementia research |