| CRISPR-Cas9 |
Gene Editing |
2012 |
A powerful tool that allows for precise modifications in the DNA of organisms. |
Medicine, Agriculture |
| Zinc Finger Nucleases (ZFNs) |
Gene Editing |
2010 |
Designed to create double-strand breaks in DNA at specific sites. |
Gene therapy, Crop improvement |
| TALENs (Transcription Activator-Like Effector Nucleases) |
Gene Editing |
2011 |
Engineered proteins that can cut DNA at specified locations, similar to ZFNs. |
Genetic modification, Therapeutics |
| Base Editing |
Gene Editing |
2016 |
Enables the conversion of one DNA base into another without causing double-strand breaks. |
Curing genetic diseases, Precision medicine |
| Prime Editing |
Gene Editing |
2019 |
Offers a versatile and precise method for directly rewriting DNA sequences. |
Gene therapy, Genetic engineering |
| CRISPR-Cas12 |
Gene Editing |
2017 |
A novel CRISPR system that offers improved specificity and reduced off-target effects. |
Diagnostics, Genetic modification |
| Gene Drives |
Gene Editing |
2015 |
A method to spread genetic alterations through populations, affecting inheritance patterns. |
Pest control, Conservation biology |
| CRISPRi/CRISPRa |
Gene Editing |
2013 |
CRISPR-based techniques to inhibit or activate gene expression without editing DNA. |
Gene regulation, Research |
| RNA-guided Gene Editing |
Gene Editing |
2019 |
Uses RNA molecules to guide editing enzymes to specific locations in the genome. |
Farmland yield enhancements, Medical research |
| Epigenome Editing |
Gene Editing |
2016 |
Techniques that allow for modifications to the epigenome and gene expression without changing DNA. |
Research, Therapeutics |
| SmRNA Molecules |
Gene Editing |
2017 |
Short modular RNA sequences used to target specific mRNA for degradation. |
Gene silencing, Precision therapeutics |
| Transgene-free Nucleases |
Gene Editing |
2020 |
Methods to edit the genome without leaving foreign DNA behind. |
Agriculture, Gene therapy |
| Gene Editing with Artificial Intelligence |
Gene Editing |
2021 |
Integration of AI algorithms with gene-editing techniques to predict outcomes and optimize edits. |
Research, Drug discovery |
| CRISPR-Cas9 in T cells |
Gene Editing |
2014 |
Adapting CRISPR-Cas9 technology to edit T cells for immunotherapy applications. |
Cancer treatment, Transplantation |
| XNA (Xeno Nucleic Acids) Technology |
Gene Editing |
2021 |
Incorporating synthetic bases into genetics to improve stability and functionality. |
Synthetic biology, Therapeutics |
| Nanoediting |
Gene Editing |
2018 |
Utilizing nanoparticles to deliver gene-editing tools directly into cells with high efficiency. |
Drug delivery, Genetic modification |
| Epigenetic therapies |
Gene Editing |
2020 |
Targeting the epigenetic modifications to alter gene expression for therapeutic purposes. |
Cancer, Neurological disorders |
| CRISPR-based diagnostics |
Gene Editing |
2016 |
Leveraging CRISPR technology for rapid and accurate disease diagnostics. |
Infectious diseases, Genetic testing |
| Microbiome Gene Editing |
Gene Editing |
2019 |
Editing the genetic material of microbiomes to enhance health benefits. |
Gut health, Probiotics |
| Cloud-based Gene Editing Services |
Gene Editing |
2022 |
Platforms providing gene-editing tools and simulations via cloud computing. |
Research, Education |
| Plant Gene Editing with CRISPR |
Gene Editing |
2016 |
Using CRISPR to improve crop resilience, nutritional value, and yield. |
Agricultural biotechnology |
| CRISPR for Sickle Cell Disease |
Gene Editing |
2020 |
Therapeutic applications of CRISPR/Cas9 to correct hemoglobin mutations. |
Genetic disorders, Hematology |
| Genome Sequencing Combined with Editing |
Gene Editing |
2018 |
Integrating sequencing technology with editing to continuously refine genetic manipulations. |
Precision medicine, Research |
| Genome-wide association studies (GWAS) integration |
Gene Editing |
2019 |
Using GWAS to inform gene editing targets and improve precision. |
Healthcare, Gene therapy |
| CRISPR-Cas13 for RNA editing |
Gene Editing |
2018 |
Editing RNA directly instead of DNA, using the CRISPR-Cas13 system. |
Viral inhibition, Gene regulation |
| Lentiviral vectors in Gene Editing |
Gene Editing |
2010 |
Viral vectors used to deliver editing tools into target cells effectively. |
Gene therapy, Genetic research |
| CRISPR-Cas9 in agriculture |
Gene Editing |
2015 |
Application of CRISPR-Cas9 for developing genetically modified crops. |
Sustainable agriculture, Crop engineering |
| Nano-Cas9 delivery systems |
Gene Editing |
2019 |
Using nanotechnology to enhance delivery of CRISPR-Cas9 into cells. |
Gene therapy, Cancer treatment |
| Chromatin-targeting CRISPR |
Gene Editing |
2019 |
Directing CRISPR systems to specific chromatin structures to modify gene regulation. |
Gene therapy, Research |
| CRISPR-mediated epigenetic modulation |
Gene Editing |
2016 |
Utilizing CRISPR technology to induce targeted epigenetic modifications. |
Therapeutics, Research |
| Biosecurity approaches in Gene Editing |
Gene Editing |
2020 |
Developing safety protocols for gene editing technologies to prevent misuse. |
Bioethics, Policy-making |
| Gene Editing for Cystic Fibrosis |
Gene Editing |
2022 |
Application of gene editing technologies to address genetic mutations associated with cystic fibrosis. |
Gene therapy, Healthcare |
| CRISPR for Huntington's disease |
Gene Editing |
2021 |
Utilization of CRISPR technology to modify genes associated with Huntington's disease. |
Therapeutics, Neurology |
| CRISPR-based plant secondary metabolite engineering |
Gene Editing |
2022 |
Editing genes related to secondary metabolites in plants to improve medicinal properties. |
Agricultural biotechnology, Pharmacology |
| Self-limiting Gene Drives |
Gene Editing |
2018 |
Gene drives designed to reduce their own spread over time to control ecological disruptions. |
Ecology, Conservation |
| Antisense Oligonucleotides with Editing |
Gene Editing |
2019 |
Novel techniques combining oligonucleotides with CRISPR for precise editing of RNA and DNA. |
Gene therapy, Neurology |
| CRISPR for gene therapy in mouse models |
Gene Editing |
2014 |
Initial use of CRISPR to demonstrate effective gene editing in mouse models for disease research. |
Research, Genetic modification |
| Virtual Reality for Gene Editing Education |
Gene Editing |
2021 |
Using virtual reality platforms to train students and researchers in gene editing techniques. |
Education, Research training |
| CRISPR for Immuno-Oncology |
Gene Editing |
2021 |
Applying CRISPR technology to enhance immune responses against cancer cells. |
Cancer therapy, Immunotherapy |
| Next-Generation Sequencing (NGS) with Editing |
Gene Editing |
2017 |
Combining NGS with gene editing to enable precise genomic analysis. |
Research, Diagnostics |
| Bioprinting with Gene Editing |
Gene Editing |
2022 |
Using gene editing in combination with bioprinting technology to create living tissues. |
Tissue engineering, Regenerative medicine |
| CRISPR-enhanced phage therapy |
Gene Editing |
2020 |
Using CRISPR technology to improve the efficacy of bacteriophage treatments for infections. |
Microbiology, Therapeutics |
| Targeted RNA degradation with CRISPR |
Gene Editing |
2018 |
Developing methods to selectively degrade RNA transcripts to control gene expression. |
Research, Gene therapy |
| Regulatory frameworks for gene editing |
Gene Editing |
2019 |
Establishing policies and regulations governing the use of gene editing technologies. |
Bioethics, Legislation |
| CRISPR and microbiome engineering |
Gene Editing |
2021 |
Utilizing CRISPR to engineer beneficial microbiomes for health applications. |
Health science, Research |
| CRISPR-assisted synthetic biology |
Gene Editing |
2020 |
Using CRISPR tools to enhance synthetic biology applications for novel organism design. |
Synthetic biology, Biotechnology |
| Invivo gene editing using CRISPR |
Gene Editing |
2017 |
Applying CRISPR technology directly into living organisms for therapeutic interventions. |
Therapeutics, Research |
| CRISPR for regenerative medicine |
Gene Editing |
2020 |
Utilizing CRISPR technology to promote healing and repair in tissues. |
Regenerative medicine, Therapeutics |
| Patient-derived models for gene editing |
Gene Editing |
2018 |
Creating models from patient cells to optimize gene editing treatments for personalized medicine. |
Healthcare, Research |
| Understanding off-target effects in gene editing |
Gene Editing |
2021 |
Research focused on identifying and minimizing unintended changes in the genome caused by editing. |
Therapeutics, Research |
| CRISPR for muscular dystrophy treatment |
Gene Editing |
2021 |
Research on using CRISPR methods to address genetic causes of muscular dystrophy. |
Gene therapy, Neurology |
| CRISPR in climate-resilient crops |
Gene Editing |
2019 |
Developing crops that can withstand climate challenges using gene editing techniques. |
Agricultural biotechnology, Food security |
| 3D modeling of genome editing pathways |
Gene Editing |
2020 |
Employing 3D modeling to visualize and understand gene editing processes and their effects. |
Research, Education |
| Using AI to predict gene editing outcomes |
Gene Editing |
2021 |
Applying machine learning algorithms to anticipate the effects of gene editing modifications. |
Research, Genomics |
| Public perceptions of gene editing technologies |
Gene Editing |
2021 |
Studying how different populations view and understand gene editing and its implications. |
Survey, Policy study |
| CRISPR for disease-resistant plants |
Gene Editing |
2019 |
Enhancing plants' natural resistance to diseases through targeted gene editing. |
Agricultural biotechnology, Crop improvement |
| Therapeutic protein development using gene editing |
Gene Editing |
2020 |
Utilizing gene editing to produce therapeutic proteins for medical treatment. |
Biotechnology, Therapeutics |
| Improving vaccine efficacy through gene editing |
Gene Editing |
2021 |
Using gene editing strategies to enhance the effectiveness of vaccines against diseases. |
Vaccinology, Infectious diseases |
| Novel CRISPR systems discovery |
Gene Editing |
2022 |
Identifying new CRISPR variants with unique properties for different applications. |
Genetic engineering, Research |
| CRISPR in fungal genetics |
Gene Editing |
2018 |
Applying CRISPR technology in research and modification of fungal species. |
Microbiology, Biotechnology |
| Designing genetic circuits with CRISPR |
Gene Editing |
2021 |
Engineering genetic circuits using CRISPR for specific cellular functions in synthetic biology. |
Synthetic biology, Genetic engineering |
| Revisional editing techniques |
Gene Editing |
2019 |
Developing methods to revise gene modifications after initial edits to ensure precision. |
Gene therapy, Research |
| CRISPR diagnostics for plant pathogens |
Gene Editing |
2020 |
Using CRISPR technologies to identify and diagnose plant diseases effectively. |
Agricultural biotechnology, Crop research |
| CRISPR-based therapeutics for liver diseases |
Gene Editing |
2021 |
Exploring CRISPR applications in treating genetic liver diseases through precise edits. |
Gene therapy, Hepatology |
| CRISPR technology profiles in diverse species |
Gene Editing |
2021 |
Documenting and analyzing the application of CRISPR techniques across various organisms. |
Research, Comparative genomics |
| Using CRISPR to improve industrial microorganisms |
Gene Editing |
2020 |
Enhancing microorganisms for industrial processes using gene editing techniques. |
Biotechnology, Industry |
| Ethics of gene editing research |
Gene Editing |
2018 |
Discussing the ethical implications and societal impacts of gene editing technologies. |
Bioethics, Policy development |
| CRISPR-mediated gene knockout innovations |
Gene Editing |
2017 |
Enhancing traditional knockout techniques using CRISPR for improved knockout studies. |
Gene therapy, Research |
| CRISPR to combat antibiotic resistance |
Gene Editing |
2021 |
Studies on using CRISPR technologies to address genetic bases of antibiotic resistance in bacteria. |
Microbiology, Healthcare |
| Genome-wide CRISPR screens |
Gene Editing |
2016 |
Utilizing CRISPR for large-scale screening of genes that impact cellular phenotypes. |
Research, Genomics |
| CRISPR and gene therapy production pipelines |
Gene Editing |
2020 |
Strategies for producing CRISPR-modified therapeutic products in a commercial setting. |
Biotechnology, Therapeutics |
| Lessons from gene editing clinical trials |
Gene Editing |
2021 |
Analyzing outcomes and lessons learned from clinical trials using gene editing in patients. |
Research, Epidemiology |
| CRISPR-enhanced cellular reprogramming |
Gene Editing |
2019 |
Using CRISPR technology to induce cellular reprogramming for therapeutic applications. |
Regenerative medicine, Transplantation |
| Low-cost CRISPR kits for educational purposes |
Gene Editing |
2022 |
Developing affordable CRISPR kits to enhance education and public engagement in gene editing. |
Education, Outreach |
| CRISPR technology's impact on agriculture |
Gene Editing |
2021 |
Evaluating how CRISPR technology is transforming agricultural practices and biosecurity. |
Agricultural economy, Policy impact |
| CRISPR systems for non-model organisms |
Gene Editing |
2018 |
Adapting CRISPR techniques for application in species that are less characterized., |
Research, Biodiversity |
| Genome editing in synthetic organisms |
Gene Editing |
2021 |
Engineering completely synthetic life forms through precise gene editing techniques. |
Synthetic biology, Scientific research |
| CRISPR-Cas9 for treating genetic disorders |
Gene Editing |
2020 |
Clinical studies exploring the potential of CRISPR-Cas9 to address genetic disorders in humans. |
Gene therapy, Clinical research |
| CRISPR-based tools for biodiversity conservation |
Gene Editing |
2022 |
Using gene editing tools to conserve endangered species and improve biodiversity. |
Conservation biology, Ecology |
| CRISPR technology in non-viral gene delivery |
Gene Editing |
2020 |
Developing non-viral methods for delivering CRISPR components into target cells. |
Gene therapy, Biotechnology |
| CRISPR manipulation of stem cells |
Gene Editing |
2016 |
Enhancing stem cell research and therapies through targeted gene editing methodologies. |
Stem cell therapy, Regenerative medicine |
| Applications of CRISPR in plant breeding |
Gene Editing |
2019 |
Innovative approaches using CRISPR to accelerate plant breeding processes and varieties development. |
Agricultural biotechnology, Crop improvement |
| Understanding gene editing impacts on ecosystems |
Gene Editing |
2021 |
Research focused on the ecological consequences of implementing gene editing technologies in nature. |
Ecology, Conservation |
| Gene editing for arachnid research |
Gene Editing |
2022 |
Utilizing gene editing to study the genetics of spiders and other arachnids for various applications. |
Research, Evolutionary biology |
| Use of soft robots in gene editing application |
Gene Editing |
2020 |
Integrating soft robotics in the delivery and operation of gene editing technologies in live experiments. |
Biotechnology, Research |
| CRISPR for myocardial repair |
Gene Editing |
2021 |
Application of gene editing strategies aimed at repairing heart tissue and preventing disease. |
Cardiology, Regenerative medicine |
| Cellular pathways optimization for gene editing |
Gene Editing |
2021 |
Optimizing cellular pathways to enhance efficiency and safety of gene editing techniques. |
Research, Biotechnology |
| Tracing CRISPR application footprints |
Gene Editing |
2019 |
Tracking the application history and progress of CRISPR technology in various fields. |
Research, Historical study |
| Building a public database for gene editing research |
Gene Editing |
2022 |
Initiating a platform for sharing data and findings related to gene editing studies globally. |
Research, Data sharing |
| Comparative analysis of editing efficiencies |
Gene Editing |
2021 |
Studying the efficiency of various gene editing techniques across different organisms. |
Research, Genomics |
| CRISPR for addressing rare genetic disorders |
Gene Editing |
2020 |
Investigating the potential of CRISPR to treat rare genetic diseases prevalent in specific populations. |
Gene therapy, Policy research |
| Integrating gene editing with biomanufacturing |
Gene Editing |
2019 |
Combining gene editing techniques with biomanufacturing processes to enhance product yield. |
Industry, Biotechnology |
| Perceptions of gene therapy in different cultures |
Gene Editing |
2021 |
Research on how cultural differences influence the understanding and acceptance of gene therapy. |
Social study, Bioethics |
| CRISPR for gut microbiome modulation |
Gene Editing |
2021 |
Using CRISPR technologies to alter gut microbiota composition for health benefits. |
Nutritional science, Microbiology |
| Real-time monitoring of gene editing outcomes |
Gene Editing |
2022 |
Employing modern techniques to monitor the effects of gene editing in real-time post-treatment. |
Research, Biotechnology |
| Collaborative frameworks in gene editing research |
Gene Editing |
2021 |
Developing partnerships between academic institutions and industry for gene editing innovations. |
Research, Collaboration |
| Novel drug delivery systems using gene editing |
Gene Editing |
2020 |
Creating innovative drug delivery methods incorporating CRISPR technologies for improved health outcomes. |
Pharmaceuticals, Biotechnology |
| Augmented reality for gene editing learning |
Gene Editing |
2022 |
Utilizing augmented reality tools to enhance the understanding of gene editing concepts in educational settings. |
Education, Technology |
| CRISPR in biomarker discovery |
Gene Editing |
2021 |
Using CRISPR technologies to identify and validate biomarkers for various diseases. |
Research, Diagnostics |
| Genomic editing in wildlife conservation |
Gene Editing |
2020 |
Applying genomic editing methods to assist in the conservation of endangered species. |
Conservation, Ecology |
| Minimizing ethical concerns in gene editing |
Gene Editing |
2021 |
Strategies for addressing the ethical dilemmas and concerns surrounding gene editing research and applications. |
Bioethics, Policy framework |
| CRISPR for cancer immunotherapy |
Gene Editing |
2021 |
Utilizing CRISPR techniques to enhance the effectiveness of immunotherapeutic approaches in cancer treatment. |
Oncology, Therapeutics |
| Exploring long-term effects of gene editing |
Gene Editing |
2022 |
Research into the long-term biological impacts of gene editing technologies in organisms. |
Research, Safety assessment |
| Development of fusion proteins for editing |
Gene Editing |
2019 |
Creating specialized fusion proteins to improve the specificity of gene editing tools. |
Biotechnology, Research |
| Ethical education in gene editing schools |
Gene Editing |
2020 |
Introducing programs to educate students about the ethics surrounding gene editing technologies. |
Education, Bioethics |
| CRISPR technologies in Alzheimer's research |
Gene Editing |
2021 |
Investigating the applications of CRISPR in the study and potential treatment of Alzheimer's disease. |
Neurology, Dementia research |